Registration results for patients 2 (top row) and 5 (bottom row). Images on the left (a,c) show an intra-procedural axial T2W image, images on the right (b,d) show the same slice of the registered preprocedure T2W MRI. Yellow contour corresponds to the outline of the prostate gland segmented in the diagnostic image and warped to the intra-procedural image space by means of registration. Images for Patient 2 show brachytherapy seeds artifacts, as the patient previously underwent radiation therapy.
Magnetic Resonance Image-guided interventions have enormous potential to improve and advance the care of men with prostate cancer. However, there are clear limitations with the current methods of both prostate cancer diagnosis and treatment. If non-invasive imaging can identify suspicious tumor foci in the gland with greater specificity, it may be used to direct more accurate prostate biopsies. A non-invasive biomarker of the tumor and its possible recurrence, combined with Prostate Specific Antigen detection methods would be a very powerful alternative to biopsy.